منابع مشابه
Absolute risk reduction due to statin use according to sex.
Downloa 3. Andreou I, Tousoulis D, Miliou A, et al. Effects of rosuvastatin on myeloperoxidase levels in patients with chronic heart failure: a randomized placebo-controlled study. Atherosclerosis 2010;210:194–8. 4. Tousoulis D, Andreou I, Tsiatas M, et al. Effects of rosuvastatin and allopurinol on circulating endothelial progenitor cells in patients with congestive heart failure: the impact o...
متن کاملMeasuring the Size of a Treatment Effect: Relative Risk Reduction, Absolute Risk Reduction, and Number Needed to Treat
Hussein Hollands, MD, MS (epid) Peter J. Kertes, MD, CM, FRCS(C) The purpose of this review article is to outline a few concepts that are useful for interpreting the results of a randomized clinical trial (RCT). Specifically, we will focus on measures of the size of a treatment effect— relative risk ratio (RRR), absolute risk ratio, and number needed to treat (NNT). These concepts are important...
متن کاملTips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat.
Physicians, patients and policy-makers are influenced not only by the results of studies but also by how authors present the results. Depending on which measures of effect authors choose, the impact of an intervention may appear very large or quite small, even though the underlying data are the same. In this article we present 3 measures of effect — relative risk reduction, absolute risk reduct...
متن کاملShould treatment recommendations for lipid lowering drugs be based on absolute coronary risk or risk reduction?
When individual variables were subjected to logistic regression, male sex, age, blood pressure, smoking status, and cholesterol concentrations were all significant predictors of heart disease but when corrected for the Framingham risk score no single factor remained predictive on its own. The figure shows the number of coronary events predicted by the Framingham model and the number observed du...
متن کاملDecision-making using absolute cardiovascular risk reduction and incremental cost-effectiveness ratios: a case study
BACKGROUND Many clinical guidelines have adopted a multifactorial cardiovascular risk assessment to identify high-risk individuals for treatment. The Framingham risk chart is a widely used risk engine to calculate the absolute cardiovascular risk of an individual. Cost-effective analyses are typically used to evaluate therapeutic strategies, but it is more problematic for a clinician when faced...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2011
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.111-2067